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Well use alerts through Optmyzr, or you can set up scripts, to scan for these anomalies so ad groups go dead for more than 1 day, cpc spikes or tanks a certain %, conversions increase or decrease a certain % etc.
This helped us not always have to be in the accounts daily and catch things a bit quicker even over the weekend we could hop in real quick since most accounts are fine and usually only a few may have an odd issue every now and then.
